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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
Drug Name
Drug ID
ATC Code
DrugBank ID
KEGG ID
PubChem ID
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ADR Ontology
ADR Term
Jaundice
ADR ID
BADD_A02422
ADR Hierarchy
01
Blood and lymphatic system disorders
01.06
Haemolyses and related conditions
01.06.04
Haemolyses NEC
01.06.04.004
Jaundice
09
Hepatobiliary disorders
09.01
Hepatic and hepatobiliary disorders
09.01.01
Cholestasis and jaundice
09.01.01.004
Jaundice
23
Skin and subcutaneous tissue disorders
23.03
Epidermal and dermal conditions
23.03.03
Dermal and epidermal conditions NEC
23.03.03.030
Jaundice
Description
A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction. [MeSH]
MedDRA Code
10023126
MeSH ID
D007565
;
D007565
;
D007565
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Icterus | Jaundice | Jaundice (excl neonatal) | Jaundice NOS | Jaundice, unspecified, not of newborn | Subicteric | Jaundice, Hemolytic | Hemolytic Jaundice | Hemolytic Jaundices | Jaundices, Hemolytic
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Alanine aminotransferase 1
P24298
Not Available
Alkaline phosphatase, tissue-nonspecific isozyme
P05186
T09538
Glutathione hydrolase 7
Q9UJ14
T25122
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00277
Bisoprolol
0.006038%
BADD_D00285
Bosentan
0.003353%
BADD_D00312
Bupropion
-
-
BADD_D00313
Bupropion hydrobromide
-
-
BADD_D00314
Bupropion hydrochloride
-
-
BADD_D00318
Busulfan
0.000533%
BADD_D00330
Cabozantinib
0.001066%
BADD_D00344
Canagliflozin
-
-
BADD_D00347
Candesartan cilexetil
0.005782%
BADD_D00349
Capecitabine
0.004529%
BADD_D00354
Captopril
0.002235%
BADD_D00356
Carbamazepine
-
-
BADD_D00360
Carbimazole
-
-
BADD_D00364
Carboplatin
-
-
BADD_D00367
Carfilzomib
-
-
BADD_D00376
Caspofungin
-
-
BADD_D00377
Caspofungin acetate
-
-
BADD_D00384
Cefdinir
-
-
BADD_D00388
Cefixime
-
-
BADD_D00390
Cefotaxime
-
-
BADD_D00391
Cefotaxime sodium
-
-
BADD_D00393
Cefoxitin
-
-
BADD_D00394
Cefoxitin sodium
-
-
BADD_D00399
Ceftazidime
-
-
BADD_D00400
Ceftazidime pentahydrate
-
-
BADD_D00401
Ceftibuten dihydrate
-
-
BADD_D00405
Ceftriaxone
0.081703%
BADD_D00406
Ceftriaxone sodium
-
-
BADD_D00407
Cefuroxime
0.000639%
BADD_D00408
Cefuroxime axetil
-
-
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